S-8

As filed with the U.S. Securities and Exchange Commission on August 10, 2023

Registration No. 333-

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM S-8

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

ATYR PHARMA, INC.

(Exact name of registrant as specified in its charter)

 

 

 

Delaware

 

20-3435077

(State or other jurisdiction of

incorporation or organization)

(I.R.S. Employer
Identification No.)

10240 Sorrento Valley Road, Suite 300

San Diego, CA 92121

(Address of Principal Executive Offices) (Zip Code)

ATYR PHARMA, INC. 2015 STOCK OPTION AND INCENTIVE PLAN, AS AMENDED

(Full title of the plan)

Sanjay S. Shukla, M.D., M.S.

President, Chief Executive Officer and Director

10240 Sorrento Valley Road, Suite 300

San Diego, CA 92121

(858) 731-8389

(Name and address of agent for service) (Telephone number, including area code, of agent for service)

 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

 

 

 

 

 

 

 

 

Large accelerated filer

Accelerated filer

 

 

 

 

Non-accelerated filer

Smaller reporting company

 

 

 

 

 

 

 

 

 

 

 

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.

 

 

 


INCORPORATION OF DOCUMENTS BY REFERENCE

 

This Registration Statement is being filed for the purpose of registering additional securities of the same class as other securities for which a Registration Statement of aTyr Pharma, Inc. (the “Registrant”) on Form S-8 relating to the same employee benefit plan is effective.

 

The Registrant previously registered shares of its Common Stock for issuance under the aTyr Pharma, Inc. 2015 Stock Option and Incentive Plan under Registration Statements on Form S-8 filed with the Securities and Exchange Commission (the “Commission”) on May 7, 2015 (File No. 333-203955), April 1, 2016 (File No. 333-210543), March 22, 2017 (File No. 333-216880), March 23, 2018 (File No. 333-223865), May 20, 2019 (File No. 333-231594), August 18, 2020 (File No. 333-248090), May 14, 2021 (File No. 333- 256145) and May 11, 2022 (File No. 333-264866) (the “Prior Registration Statements”).

 

Pursuant to General Instruction E to Form S-8, this Registration Statement hereby incorporates by reference the contents of the Prior Registration Statements and the description of the Registrant’s Common Stock which is contained in a Registration Statement on Form 8-A filed with the Commission on May 6, 2015 (File No. 001-37378) under Section 12(b) of the Securities Exchange Act of 1934, as amended, including any amendment or report filed for the purpose of updating such description, including Exhibit 4.9 to the Registrant’s Annual Report on Form 10-K for the fiscal year ended December 31, 2022, as filed with the Commission on March 14, 2023.

2

 


Item 8. Exhibits.

The exhibits to this Registration Statement are listed below:

 

Incorporated by Reference

 

Exhibit

Number

Exhibit Title

Form

File No.

Exhibit

Filing Date

3.1

Restated Certificate of Incorporation of the Registrant

10-Q

001-37378

3.1

November 14, 2022

3.2

Certificate of Amendment to Restated Certificate of Incorporation of the Registrant

8-K

001-37378

3.1

June 28, 2019

3.3

Certificate of Amendment to Restated Certificate of Incorporation of the Registrant

10-Q

001-37378

3.3

May 12, 2020

3.4

Certificate of Amendment to Restated Certificate of Incorporation of the Registrant

8-K

001-37378

3.1

May 4, 2021

3.5

Certificate of Amendment to Restated Certificate of Incorporation of the Registrant

8-K

001-37378

3.1

April 29, 2022

3.6

Certificate of Amendment to Restated Certificate of Incorporation of the Registrant

8-K

001-37378

3.1

May 19, 2023

3.7

Amended and Restated Bylaws of the Registrant

10-Q

001-37378

3.6

November 14, 2022

4.1

Specimen Common Stock Certificate

S-1/A

333-203272

4.1

April 27, 2015

4.2

Warrant to Purchase Stock issued to Silicon Valley Bank on November 18, 2016

10-K

001-37378

4.5

March 16, 2017

4.3

Warrant to Purchase Stock issued to Solar Capital Ltd. on November 18, 2016

10-K

001-37378

4.6

March 16, 2017

4.4

Warrant to Purchase Stock issued to Silicon Valley Bank on June 30, 2017

10-Q

001-37378

4.7

August 14, 2017

4.5

Warrant to Purchase Stock issued to Solar Capital Ltd. on June 30, 2017

10-Q

001-37378

4.8

August 14, 2017

4.6

Warrant to Purchase Stock issued to Silicon Valley Bank on December 22, 2017

10-K

001-37378

4.8

March 20, 2018

4.7

Warrant to Purchase Stock issued to Solar Capital Ltd. on December 22, 2017

10-K

001-37378

4.9

March 20, 2018

5.1

Opinion of Cooley LLP

Filed herewith

23.1

Consent of Cooley LLP (included in Exhibit 5.1)

Filed herewith

23.2

Consent of Independent Registered Public Accounting Firm

Filed herewith

24.1

Power of Attorney (included on the signature page hereto)

Filed herewith

99.1

aTyr Pharma, Inc. 2015 Stock Option and Incentive Plan, as amended

8-K

001-37378

10.1

May 19, 2023

107

Filing Fee Table

Filed herewith

 

3

 


SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of San Diego, State of California, this 10th day of August, 2023.

 

 

 

 

ATYR PHARMA, INC.

 

 

 

 

By:

/s/ Sanjay S. Shukla

 

 

Sanjay S. Shukla, M.D., M.S.

 

 

President, Chief Executive Officer and Director

 

POWER OF ATTORNEY AND SIGNATURES

We, the undersigned officers and directors of aTyr Pharma, Inc., hereby severally constitute and appoint Sanjay S. Shukla, M.D., M.S. and Jill M. Broadfoot, and each of them singly (with full power to each of them to act alone), our true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution in each of them for their and in their name, place and stead, and in any and all capacities, to sign for us and in our names in the capacities indicated below any and all amendments (including post-effective amendments) to this registration statement on Form S-8, and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite or necessary to be done in and about the premises, as full to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or any of them, or their or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the date indicated below.

 

 

 

 

Signature

Title

Date

 

 

 

/s/ Sanjay S. Shukla

President, Chief Executive Officer and Director

August 10, 2023

Sanjay S. Shukla, M.D., M.S.

(Principal Executive Officer)

 

 

 

 

/s/ Jill M. Broadfoot

Chief Financial Officer

August 10, 2023

Jill M. Broadfoot

(Principal Financial and Accounting Officer)

 

 

 

 

/s/ John K. Clarke

Chairman of the Board and Director

August 10, 2023

John K. Clarke

 

 

 

 

 

/s/ Jane A. Gross

Director

August 10, 2023

Jane A. Gross, Ph.D.

 

 

 

 

 

/s/ Timothy P. Coughlin

Director

August 10, 2023

Timothy P. Coughlin

 

 

 

 

 

 

 

/s/ Svetlana Lucas

Director

 

August 10, 2023

Svetlana Lucas, Ph.D.

 

 

 

 

 

 

 

 

/s/ Paul Schimmel

Director

 

August 10, 2023

Paul Schimmel, Ph.D.

 

 

 

 

 

 

 

/s/ Sara L. Zaknoen

Director

 

August 10, 2023

Sara L. Zaknoen, M.D.

 

 

 

4

 


EX-5.1

https://cdn.kscope.io/a353d6d075ad02ed8383eea376f09d36-img106332022_0.jpg 

Exhibit 5.1

 

Charles J. Bair

+1 858 550 6142

cbair@cooley.com

August 10, 2023

aTyr Pharma, Inc.

10240 Sorrento Valley Road, Suite 300

San Diego, CA 92121

 

Ladies and Gentlemen:

You have requested our opinion, as counsel to aTyr Pharma, Inc., a Delaware corporation (the “Company”), in connection with the filing by the Company of a Registration Statement on Form S-8 (the “Registration Statement”) with the Securities and Exchange Commission (the “Commission”) covering the offering of up to 4,000,000 shares (the “Shares”) of the Company’s common stock, $0.001 par value per share (“Common Stock”), issuable pursuant to the Company’s 2015 Stock Option and Incentive Plan, as amended (the “Plan”).

 

In connection with this opinion, we have examined and relied upon the Registration Statement and related prospectuses, the Plan, the Company’s certificate of incorporation and bylaws, each as currently in effect, and such other records, documents, certificates, memoranda and other instruments as in our judgment are necessary or appropriate to enable us to render the opinion expressed below. We have assumed the genuineness of all signatures, the authenticity of all documents submitted to us as originals, the conformity to originals of all documents submitted to us as copies, the accuracy, completeness and authenticity of certificates of public officials and the due authorization, execution and delivery of all documents by all persons other than by the Company where authorization, execution and delivery are prerequisites to the effectiveness thereof. As to certain factual matters, we have relied upon a certificate of an officer of the Company and have not independently verified such matters.

 

Our opinion is expressed only with respect to the General Corporation Law of the State of Delaware. We express no opinion to the extent that any other laws are applicable to the subject matter hereof and express no opinion and provide no assurance as to compliance with any federal or state securities law, rule or regulation.

 

On the basis of the foregoing, and in reliance thereon, we are of the opinion that the Shares, when sold and issued in accordance with the Plan, the Registration Statement and related prospectuses, will be validly issued, fully paid and nonassessable (except as to Shares issued pursuant to deferred payment arrangements, which will be fully paid and nonassessable when such deferred payments are made in full).

 

This opinion is limited to the matters expressly set forth in this letter, and no opinion should be implied, or may be inferred, beyond the matters expressly stated. This opinion speaks only as to law and facts in effect or existing as of the date hereof and we undertake no obligation or responsibility to update or supplement this letter to reflect any facts or circumstances that may hereafter come to our attention or any changes in law that may hereafter occur.

 

We consent to the filing of this opinion as an exhibit to the Registration Statement. In giving such consent, we do not thereby admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act of 1933, as amended, or the rules and regulations of the Commission thereunder.

Sincerely,

Cooley LLP

By: /s/ Charles J. Bair

Charles J. Bair

Cooley LLP 10265 Science Center Drive San Diego, CA 92121
T: (858) 550-6000 F: (858) 550-6420 cooley.com


EX-23.2

Exhibit 23.2

 

Consent of Independent Registered Public Accounting Firm

 

We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the aTyr Pharma, Inc. 2015 Stock Option and Incentive Plan, as amended, of our report dated March 14, 2023, with respect to the consolidated financial statements of aTyr Pharma, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2022, filed with the Securities and Exchange Commission.

 

/s/ Ernst & Young LLP

 

San Diego, California

August 9, 2023

 


EX-FILING FEES

Exhibit 107

Calculation of Filing Fee Table

 

Form S-8

(Form Type)

 

aTyr Pharma, Inc.

(Exact Name of Registrant as Specified in its Charter)

 

Table 1: Newly Registered Securities

 

Security Type

Security Class Title

Fee Calculation Rule

Amount Registered(1)

Proposed Maximum Offering Price Per Share

 Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Equity

2015 Stock Option and Incentive Plan, as amended

Common Stock, par value $0.001 per share

Other(2)

4,000,000(3)

$ 1.98(2)

$ 7,920,000.00

.0001102

$872.78

Total Offering Amounts

 

$ 7,920,000.00

 

$872.78

Total Fee Offsets

 

 

 

Net Fee Due

 

 

 

$872.78

 

(1)

Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement shall also cover any additional shares of common stock, par value $0.001 per share (“Common Stock”), of aTyr Pharma, Inc. (the “Registrant”) that become issuable under the aTyr Pharma, Inc. 2015 Stock Option and Incentive Plan, as amended (the “2015 Stock Plan”), by reason of any stock dividend, stock split, recapitalization or other similar transaction.

(2)

This estimate is made pursuant to Rule 457(h)(1) and Rule 457(c) under the Securities Act solely for purposes of calculating the registration fee. The price per share and aggregate offering price are based upon the average of the high and low prices of the Registrant's Common Stock on August 7, 2023, as reported on the Nasdaq Capital Market.

(3)

Represents 4,000,000 additional shares of Common Stock reserved and available for issuance under the 2015 Stock Plan, as approved by the Registrant’s stockholders at its annual meeting of stockholders on May 17, 2023 (the “2023 Annual Meeting”). At the 2023 Annual Meeting, the Registrant’s stockholders approved an amendment to the 2015 Stock Plan to increase the maximum number of shares of Common Stock reserved and available for issuance under the 2015 Stock Plan by 4,000,000 shares.